摘要
目的：研究丹参多酚酸联合低分子肝素钠治疗急性期脑梗死并发抑郁症的临床效果。方法：选取我院从2013年1月至2015年1月收治的急性期脑梗死并发抑郁症患者96例，采用随机数字表法将96例急性期脑梗死并发抑郁症患者分为观察组（48例）和对照组（48例）；观察组采取口服丹参多酚酸钙片联合低分子肝素钠的方式进行治疗，对照组采取单独口服低分子肝素钠的方式进行治疗，将两组患者临床疗效以及血脂水平进行观察对比并进一步分析。结果 观察组临床有效率为91.67（44/48），对照组的临床有效率为75.00%（36/48），组间比较差异具有统计学意义（P＜0.05）。在治疗前HAMA评分以及HAMD评分比较差异无统计学意义（P>0.05）；治疗后此两项评分与组间评分差异均较大（P<0.05）。结论：丹参多酚酸联合低分子肝素钠治疗脑梗死并抑郁症明显提高临床治疗效果，具有一定的安全性，因此值得临床推荐。
关键词： 丹参多酚酸；低分子肝素钠；脑梗死；抑郁症
Abstract
Objective: To study the clinical effect of combined with low molecular weight heparin sodium in the treatment of acute cerebral infarction with cerebral infarction and depression, and to study the clinical effect of low molecular weight heparin sodium in the treatment of acute cerebral infarction. Methods: Using in our hospital from January 2013 to 2015 January acute cerebral infarction complicated with depression in patients with 96 cases, using random number table method will 96 cases at acute stage of cerebral infarction complicated with depression were divided into observation group (48 cases) and control group (48 cases); observation group taking oral salvianolic acid calcium combined with low molecular weight heparin sodium treatment, the control group took single oral low molecular weight heparin sodium treatment, the clinical curative effect of two groups of patients and blood lipid levels were observed and compared and subjected to further analysis. Results the clinical effective rate of the observation group was 91.67 (44/48), the clinical effective rate of the control group was 75% (36/48), the difference was statistically significant (P < 0.05). There was no significant difference in HAMA score and HAMD score before treatment (P>0.05); the difference between the two scores and the scores of the treatment group was significantly higher (P<0.05).Conclusion : Combined with low molecular weight heparin sodium for treatment of cerebral infarction and depression, it has a certain safety, so it is worthy of clinical recommendation.
Key words： Low molecular weight heparin; low molecular weight heparin sodium; cerebral infarction; depression
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