Application of whole body motion assessment combined with brain function monitoring in the early diagnosis of neonatal brain injury
全身运动评估联合脑功能监测在新生儿脑损伤早期诊断中的应用

摘要

目的 研究全身运动（GMs）评估联合脑功能监测在新生儿脑损伤早期诊断中的应用。方法 为达成实验目的，选取经脑损伤金标准诊断后确认为脑损伤的79例高危患儿作为研究对象，分别对其进行GMs、振幅整合脑电图（aEEG）进行检查，比较两种方法对新生儿脑损伤的早期诊断准确率，同时探究两种方法联合检查的诊断准确率。结果 经“金标准”方法检查诊断后，确认79例脑损伤患儿中51例正常，23例运动发育迟缓，5例脑瘫；通过GMs进行检查时发现，在扭动运动阶段有26例PR异常和3例CS异常，其余50例正常；不安运动阶段中，确认有F+正常73例，其余6例为异常，并包括有3例脑瘫。其次，在aEEG检查时发现，正常患儿53例，轻度异常21例，5例重度异常。结论 两种方法对新生儿脑损伤的诊断准确性均较高，将GMs+aEEG应用于新生儿脑损伤诊断中有较高的灵敏度和准确率，应用价值极高。

Abstract

Objective: To study the application of whole body movement (GMs) assessment combined with brain function monitoring in the early diagnosis of neonatal brain injury.
Methods: In order to achieve the purpose of the experiment, 79 high-risk children diagnosed with brain injury after the brain injury gold standard diagnosis were selected as the research objects, and the GMs and amplitude integrated electroencephalogram (aEEG) were examined respectively, and the two methods were compared. The accuracy rate of early diagnosis of neonatal brain injury, and at the same time explore the diagnostic accuracy rate of the combined examination of the two methods.
Results: After diagnosis by the "gold standard" method, 51 cases of 79 children with brain injury were confirmed to be normal, 23 cases of motor development retardation, and 5 cases of cerebral palsy. When checked by GMs, it was found that there were 26 cases of PR in the twisting movement stage. There were abnormalities and 3 cases of CS abnormality, and the remaining 50 cases were normal. During the restless movement stage, 73 cases of F+ normal were confirmed, and the remaining 6 cases were abnormal, including 3 cases of cerebral palsy. Secondly, during the aEEG examination, it was found that 53 cases of normal children, 21 cases of mild abnormalities, and 5 cases of severe abnormalities.
Conclusion  : Both methods have high accuracy in the diagnosis of neonatal brain injury. The application of GMs+aEEG in the diagnosis of neonatal brain injury has high sensitivity and accuracy, and its application value is extremely high.